Journal of International Reproductive Health/Family Planning ›› 2015, Vol. 34 ›› Issue (6): 514-518.

• 综述 • Previous Articles     Next Articles

Research Progress of Fertility Preservation Treatment in Patients with Borderline Ovarian Tumors

LI Shu-chang,LU Mei-song   

  1. The First Affiliated Hospital of Harbin Medical University, Harbin 150006, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-11-15 Online:2015-11-15
  • Contact: LU Mei-song

Abstract: Borderline ovarian tumors(BOTs) are characterized by the histopathologic feature and biologic behavior which intermediate between clearly benign and frankly malignant ovarian tumors. The patients are young women, with a trend of younger, one-third of them have not completed childbearing. Because of BOTs′ unique pathological and clinical characteristics, the diagnosis and management of BOTs are different from those of ovarian cancer. For those young patients with BOTs, the fertility preservation surgery is the best option. This conservative surgery is still relatively safe, because the success rate of fertility is higher and the mortality of BOTs recurrence of conservative surgery is not increased although the recurrence rate is higher than that of non-conservative surgery. The detailed surgical option should be based on the individual circumstance. Chemotherapy should not be recommended as a routine. The complications followed by pregnancy are few,and pregnancy seems to have little impact on disease progression. The assisted reproductive technology can improve the pregnancy outcome in those BOTs patients after fertility preservation operation. The ovulation induction can be used in those patients with early-stage BOTs after fertility preservation operation, however it should be carefully used in those patients with advanced-stage BOTs.

Key words: Ovarian neoplasms, Fertility, Clinical protocols, Pregnancy outcome, Reproductive techniques, assisted, Borderline tumor