Abstract: Objective：To investigate the clinical effect of the emergency cervical cerclage combined with atosiban in the treatment of cervical incompetence. Methods：A total of 27 patients with cervical incompetence, who were treated with emergency cervical cerclage and atosiban between January 2013 to December 2015, were analyzed retrospectively. Clinical effect, pregnancy outcome and maternal adverse events were assessed. Results：The combining treatment can effectively extend the gestational age for (8.6±5.4) weeks, with the delivery age (31.8±4.7) weeks and the total live birth rate 74.1% (20/27). The efficacy of atosiban on uterine contraction was 62.9% (17/27). Only four patients presented atosiban-related side effects, three of them presented with mild nausea and vomiting and one patient mild headache. No case discontinued atosiban because of drug-related side effects. Conclusions：The combination of atosiban with emergency cervical cerclage for the treatment of cervical incompetence can effectively extend the gestational age at delivery, and improve the pregnancy outcome.

Key words: Cerclage, cervical, Uterine cervical incompetence, Atosiban