The Effect and Mechanism of Epimedium (Icariin) on Male Reproductive System

doi:10.12280/gjszjk.20220051

Abstract

Abstract:

Epimedium is a commonly used traditional Chinese medicine. Icariin as a flavonoid extracted from Epimedium is the main active substance in Epimedium. It is found that Icariin has many functions, such as promoting the formation and activation of osteoblasts, regulating immunity, anti-aging, anti-inflammatory and so on. Clinically, Epimedium(Icariin) is used to treat many diseases of reproductive system, bone and joint, respiratory system, nervous system, cardiovascular system, immune system and other. This paper summarizes the effects and mechanisms of Epimedium(Icariin) on male reproductive system. Epimedium(Icariin) plays an androgen-like effect by itself, and promotes the synthesis and secretion of testicular testosterone. Icariin can promote the production of sperm, increase sperm density, improve sperm motility, and slow down reproductive decline by improving the microenvironment of spermatogenesis and antioxidation. In addition, Epimedium(Icariin) is also used to treat the erectile dysfunction and premature ejaculation by promoting penile erection.

Key words: Epimedium brevicornum, Icariin, Genital diseases,male, Infertility,male, Therapy

LI Cheng, CUI Yu-gui, QIN Lian-ju, HU Wen-jun. The Effect and Mechanism of Epimedium (Icariin) on Male Reproductive System[J]. Journal of International Reproductive Health/Family Planning, 2022, 41(3): 236-239.

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