Biological and Clinical Characteristics of Obese PCOS Patients

doi:10.12280/gjszjk.20220067

Abstract

Abstract:

Polycystic ovary syndrome (PCOS) is an endocrine and metabolic syndrome with highly heterogeneous manifestations. Obesity is one of the heterogeneous manifestations of PCOS, and more than 50% of PCOS patients are overweight or obese. Obese PCOS is characterized mainly by hyperandrogenism, central obesity and disturbed glucose and lipid metabolism, while non-obese PCOS is characterized mainly by abnormally elevated level of luteinizing hormone (LH). Although the endocrine metabolic abnormalities are present in both obese and non-obese PCOS, obesity exacerbates the disturbed glycolipid metabolism in PCOS patients. The obese PCOS also expresses the abnormality of lipid metabolism. In this review, we summarizethe clinical features, sex hormone levels and glycolipid metabolism of obese PCOS patients, so as to provide a reference for the new diagnosis and treatment of obese and non obese patients with PCOS.

Key words: Polycystic ovary syndrome, Obesity, Gonadal steroid hormones, Glucose metabolism disorders, Lipid metabolism disorders

WANG Jiao-jian, LU Di, CHEN Ran-ran, SONG Dian-rong. Biological and Clinical Characteristics of Obese PCOS Patients[J]. Journal of International Reproductive Health/Family Planning, 2022, 41(3): 230-235.

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