Abstract:

Cellular leiomyoma is a rare borderline tumor that occurs in the uterus, while cellular leiomyoma that occur in the vulva (cellular vulva leiomyoma) is more rare in the clinic. The location and clinical manifestations of leiomyomas located in the vestibular glands are very similar to those of Bartholin′s gland cysts, so these leiomyomas are often misdiagnosed as Bartholin′s gland cysts in clinical practice. Pathological examination is the main method for definite diagnosis. Compared with ordinary leiomyoma, cellular leiomyomas in histopathologic examination show the braided arrangement phenomenon and abundant cytoplasm. However, there is no significant difference in the cell size and morphology. Recently, a patient with a cellular vulvar leiomyoma was diagnosed and treated in the First Affiliated Hospital of Guangzhou University of Chinese Medicine. The patient was first diagnosed as the Bartholin′s gland cyst according to the history, symptoms and signs. The "cyst" was surgically excised, and for the histological examination and immunohistochemical examination confirmed the diagnosis of a cellular vulvar leiomyoma. MRI and colour ultrasound may help the clinician to make a differential diagnosis, while the definite diagnosis mostly requires pathological examination.

Key words: Vulvar neoplasms, Leiomyoma, [Bartholin′s] glands, Cysts, Diagnosis, differential, Immunohistochemistry