Journal of International Reproductive Health/Family Planning ›› 2018, Vol. 37 ›› Issue (1): 62-65.

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Clinical Research Progress of Ovarian Response Predictors

KE Jia-min, XIA Wei, SU Ning, LUO Xiao-huan   

  1. Reproductive Health and Infertility Special Department, Guangzhou First People′s Hospital, Guangzhou Medical University, Guangzhou 510180, China
  • Received:2017-12-01 Revised:2018-01-09 Published:2018-01-15 Online:2018-02-02
  • Contact: XIA Wei, E-mail:rose-xw@163.com E-mail:1149928934@qq.com

Abstract: Ovarian response refers to the response of the follicle to the exogenous gonadotropin during the controlled ovarian stimulation (COS). In assisted reproductive technology, COS is the key and difficult step. In clinic, some parameters were used as the predictors of ovarian response during COS, and as the reference of the optimized schedule and individual treatment so as to obtain an ideal outcome of in vitro fertilization/intra-cytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET). Some of common ovarian response predictors were evaluated in this review, such as age, basal follicle stimulating hormone (FSH), basal FSH/basal LH ratio, basal estradiol, inhibin B, anti-Mullerian hormone (AMH), follicular output rate and the antral follicle count, in which the evaluation mainly included the ovarian responsiveness and the outcome of IVF/ICSI-ET, as well as their advantages and limitations in clinical application. Meanwhile, the future development of those ovarian response predictors was also proposed.

Key words: Ovarian response, Ovary, Reproductive techniques, assisted, Follicular output rate, Ovarian follicle