Abstract:  Objective: To investigate the cognition and attitude towards HPV and HPV vaccination among community workers and primary medical stuffs in a township of Shanghai, and to provide some basic information for the HPV vaccine promotion. Methods：All stuffs from each neighborhood committee and medical stuffs from two Community Health Service Centers in Gaoqiao Township of Shanghai were investigated using the designed questionnaire. Results：On the whole, the basic knowledge of HPV in community doctors was better than that in community workers (P＜0.05). However, there was no significant difference in the knowledge of HPV transmission routes (81.81% vs. 85.79%) and risk factors (31.06% vs. 39.47%) between the two groups （P＞0.05）. Significant differences  were also found in the vaccination intention of themselves, sex partners or daughters; the acceptable sources, payment way and price, and the location of HPV vaccine injection between the two groups (P＜0.05). Community workers were more likely to vaccinate themselves or their spouses, and to accept the vaccine certified by the government and low cost. Relative with cancer (direct relative and collateral relative within three generations) was a factor associated with inoculate willingness (OR=4.006, 95%CI: 2.071-7.747, P=0.000). Conclusions：It is important to strengthen the knowledge of HPV prevention measures and infection factors among community workers and medical stuffs. The publicity of HPV vaccine should be focused on its safety and efficacy. The promotion of HPV vaccine should be based on the different background of population. The government should get involved in the procurement of vaccines, and manage the large-scale procurement.

Key words: Uterine cervical neoplasms, Papillomaviridae, Papillomavirus vaccines, Risk factors, Cognition, Vaccination