Journal of International Reproductive Health/Family Planning ›› 2022, Vol. 41 ›› Issue (1): 42-45.doi: 10.12280/gjszjk.20210383

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Research Progress of Cervical Incompetence in Assisted Reproduction Technology

NI Dan-yu, JI Hui, XIE Qi-jun, LING Xiu-feng()   

  1. Reproductive Medicine Center, Women′s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, China
  • Received:2021-08-23 Published:2022-01-15 Online:2022-02-17
  • Contact: LING Xiu-feng E-mail:lingxiufeng_njfy@163.com

Abstract:

Cervical incompetence (or cervical insufficiency, CI) is an important cause of miscarriage and preterm delivery in the middle and third trimester of pregnancy. Compared with women who conceived naturally, patients who received assisted reproductive technology (ART) had a higher risk of CI. The high risk factors of CI following ART may be related to polycystic ovary syndrome (PCOS), uterine malformation, cervical mechanical injury, fertility drugs, multiple pregnancies and so on. CI following ART can be early prevented through multiple measures, such as single embryo transfer, full promotion of softening and maturation before cervical operation and weight quality management. At present, there are a variety of clinical treatment methods for CI, including bed rest, vaginal progesterone suppository, cervical bracket and cervical cerclage and so on. For patients with short cervix of recurrent abortion, after excluding the inducing factors of CI, it is recommended that prophylactic laparoscopic uterine cervical isthmus cerclage at 12-14 weeks of pregnancy is of great significance to improve the clinical pregnancy rate of ART.

Key words: Uterine cervical incompetence, Reproductive techniques, assisted, Infertility,female, Polycystic ovary syndrome, Cerclage,cervical