基于“心肾相交”理论探讨情志因素在辅助生殖中的应用

doi:10.12280/gjszjk.20250572

摘要/Abstract

摘要：

辅助生殖技术（assisted reproductive technology，ART）现已广泛用于不孕症的治疗，其总体成功率保持在30%~40%。除年龄、生理与病理等因素外，情志压力作为一项可调节的影响因素，日益受到重视。现代医学常从“心理-神经-内分泌-免疫”网络角度解释情志因素的作用机制，而中医学中的“心肾相交”理论深刻揭示了精神心理（心）与生殖功能（肾）之间相互促进、相互制约的动态平衡关系，为理解情志因素对ART治疗全程的影响提供了独特视角与多样化的干预思路。通过系统梳理“心肾相交”理论的内涵，分析思虑过度、恐惧惊悸、郁怒不解等情志失调状态如何破坏“心肾水火既济”的平衡，形成“心肾不交”这一核心病机，并进一步通过精血亏耗、虚火上炎、神志不宁及胞宫滞涩等环节最终影响卵泡发育、胚胎质量及子宫内膜容受性。提出以“交通心肾”为核心的综合干预策略，涵盖中药、针灸、情志调摄等方面，为临床上将情志调节用于不孕症的ART治疗提供理论参考与实践路径，促进中西医在生殖医学领域的进一步融合。

关键词: 心肾相交, 情志疗法, 生殖技术，辅助, 心肾不交, 中医理论基础

Abstract:

Assisted reproductive technology (ART) has been widely used for the treatment of infertility, with an overall success rate of 30% to 40%. Beyond age, physiological and pathological factors, the emotional stress is increasingly recognized as a significant and modifiable factor influencing ART outcomes. Modern medicine explains the action mechanism of emotional factors through the psycho-neuro-endocrine-immune network. While in traditional Chinese medicine, the theory of "intercourse between heart and kidney" provides a profound perspective on the dynamic balance between mental and emotional states (heart) and reproductive function (kidney). This relationship involves both mutual promotion and restraint, offering a distinctive lens through which to examine how emotions affect ART treatment throughout the entire process, along with diverse intervention strategies. This article systematically outlines the theoretical basis of "intercourse between heart and kidney", analyzes how emotional imbalances, such as excessive worry, fear, fright, or unresolved anger, can disrupt the harmonious balance between the heart and kidneys, leading to the core pathogenesis known as "disharmony between heart and kidney". This disruption may contribute to essence deficiency, hyperactivity of fire, mental agitation, and uterine stagnation, ultimately impairing follicular development, embryo quality and endometrial receptivity. Based on the principle of "restoring heart-kidney communication", the integrated treatment strategies include Chinese herbal medicine, acupuncture, emotional regulation and other holistic approaches, as theoretical reference and practical insights for the use of emotional regulation in ART treatment of infertility in clinical practice, thereby fostering deeper integration of Chinese and Western medicine in the field of reproductive medicine.

Key words: Intercourse between heart and kidney, Emotional therapy, Reproductive techniques, assisted, Syndrome of disharmony between heart and kidney, Rationale of TCM science

潘可盈, 王月, 张骞文, 王如意, 蒋兴月, 张虹艳, 赵帅. 基于“心肾相交”理论探讨情志因素在辅助生殖中的应用[J]. 国际生殖健康/计划生育杂志, 2026, 45(1): 83-88.

PAN Ke-ying, WANG Yue, ZHANG Qian-wen, WANG Ru-yi, JIANG Xing-yue, ZHANG Hong-yan, ZHAO Shuai. Exploring the Application of Emotional Factors in Assisted Reproduction Based on the "Intercourse between Heart and Kidney" Theory[J]. Journal of International Reproductive Health/Family Planning, 2026, 45(1): 83-88.

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