国际生殖健康/计划生育 ›› 2012, Vol. 31 ›› Issue (1): 71-74.

• 综述 • 上一篇    下一篇

影响体外受精胚胎种植环境的研究进展

张姹慧,蔡 霞   

  1. 830054  新疆医科大学第一附属医院生殖中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-01-15 发布日期:2012-01-15

Environment of Embryo Implantation in IVF

ZHANG Cha-hui, CAI Xia   

  1. Reproductive Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-01-15 Online:2012-01-15

摘要: 体外受精-胚胎移植(IVF-ET)的临床妊娠率受多方面因素的影响,其中,胚胎种植环境是IVF治疗结局的重要因素。随母亲年龄增长、体质量指数(BMI)的增加子宫内膜容受性降低,影响胚胎种植环境,使临床妊娠率和胎儿成活率降低,自然流产率增加。从年龄、BMI、子宫内膜容受性和细胞因子方面就IVF-ET胚胎种植环境的影响因素等相关研究进行综述。

关键词: 受精, 体外, 胚胎移植, 母亲年龄, 人体质量指数, 子宫内膜, 妊娠相关血浆蛋白A, HLA抗原, 白细胞介素18

Abstract: The pregnancy rate of IVF-ET is affected by many factors, of which environment of embryo implantation in IVF is an important factor for the treatment outcome. The woman's age and BMI index have a negative effect on the embryo implantation environment and pregnancy rates by decreasing endometrial recepitivity. It is speculated that embryo implantation environment has an effect on embryo quality and endometrial recepitivity. This article reviewed the research progress of IVF-ET embryo implantation environment, and effects of age, BMI, endometrial receptivity and cellular factors on the implantation environment.