国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2012, Vol. 31 ›› Issue (3): 239-241.

• 综述 • 上一篇    下一篇

输卵管积水对辅助生殖影响机制的研究进展

刘 艳,孙莹璞   

  1. 450052 郑州大学第一附属医院生殖中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-05-15 发布日期:2012-05-15
  • 通讯作者: 孙莹璞

Effect of Hydrosalpinx on ART Outcomes and Mechanisms

LIU Yan，SUN Ying-pu   

  1. Reproductive Center of the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-05-15 Online:2012-05-15
  • Contact: SUN Ying-pu

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摘要： 多项流行病学研究显示，输卵管因素占女性不孕因素的30%～40%，其中输卵管积水是输卵管因素的一个重要组成部分。输卵管积水对辅助生殖技术临床结局的主要影响可能在于：机械性冲刷、胚胎毒性、降低子宫内膜容受性、抑制卵巢功能、降低子宫内膜及内膜下血流、改变精子运动及抑制受精过程等。通过分析输卵管积水对辅助生殖结局的影响机制，可以为输卵管积水患者制定治疗方案做出指导。

关键词: 输卵管疾病, 水肿, 不育, 女（雌）性, 生殖技术, 辅助, 妊娠结局

Abstract: Epidemiological studies showed that 30%-40% of female infertility were accounted for oviduct diseases. Hydrosalpinx was one of main oviduct diseases. Effect of hydrosalpinx on ART outcomes and its pathophysiological mechanisms could be summarized as follows, mechanical washing, embryo toxicity, lowered endometrial receptivity, inhibited ovarian function, loss blood flow in and beneath endometrium, restricted sperm activity and fertilization. By reviewing the effect of hydrosalpinx on ART outcomes, we can provide better strategies of ART treatment for patients with hydrosalpinx.

Key words: Fallopian tube diseases, Edema, Infertility, female, Reproductive techniques, assisted, Pregnancy outcome