国际生殖健康/计划生育 ›› 2017, Vol. 36 ›› Issue (1): 18-21.

• 论著 • 上一篇    下一篇

不孕人群与正常人群妊娠并发症及围生结局的比较

钱春凤1,李红2   

  1. 1. 南京医科大学附属苏州医院,苏州市立医院
    2. 南京医科大学附属苏州医院
  • 收稿日期:2016-08-29 修回日期:2016-12-12 出版日期:2017-01-15 发布日期:2017-03-29
  • 通讯作者: 李红 E-mail:hongliszivf@163.com

Obstetric and perinatal outcomes in infertile women and general women

1,   

  • Received:2016-08-29 Revised:2016-12-12 Published:2017-01-15 Online:2017-03-29

摘要: 【摘要】目的:探讨不孕夫妇的不孕背景对妊娠并发症及围生结局的影响。方法:对2014年6月—12月在南京医科大学附属苏州医院(本院)入院待产的1 000名产妇进行自制问卷调查。其中备孕时间超过1年、单胎且未行辅助生殖技术(ART)者136名作为不孕症史组;备孕时间未超过1年、单胎、且与不孕症史组的年龄、产次、分娩方式严格按照1?2匹配的272名产妇为正常对照组;在本院生殖中心行体外受精/胞浆内单精子注射(IVF/ICSI)治疗同期本院分娩的114名产妇为ART组。比较各组的妊娠并发症及围生结局。结果:不孕症史组低出生体质量儿发生率(11.03% vs. 5.15%)高于正常对照组,差异有统计学意义(P<0.05)。结论:不孕夫妇的不孕背景可能影响了新生儿的低出生体质量的发生率。

关键词: 不育;女(雌)性, 妊娠并发症, 妊娠结局, 早产, 婴儿;出生时低体重, 婴儿;小于胎龄

Abstract: 【Abstract】Objective: To investigate the background of infertility on the obstetric and perinatal outcomes. Methods: A total of 1 000 delivery women were investigated in Nanjing Medical University Affiliated Suzhou Hospital from June 1st, 2014 to December 31th, 2014 by self-designed questionary. Among these women, 136 women were defined infertility group as those who conceived over one year of normal sex life and had not received any assisted reproductive technology (ART). 272 women were selected as control group according to 1:2 matched method by matching singleton, age, parity, delivery method. 114 women who received IVF/ICSI and delivered in our hospital at the same period were defined ART group.Obstetric and perinatal outcomes were compared among these groups. Results: The incidence of low birth weight(11.03% vs. 5.15%) was significantly higher in the infertility group than in the control group(P<0.05). Conclusions: The infertility background affects the rate of low birth weight of newborns.

Key words: Infertility;female, Pregnancy complications, Pregnancy outcome, Premature birth, Infant;low birth weight, Infant;small for gestational age

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