国际生殖健康/计划生育 ›› 2017, Vol. 36 ›› Issue (2): 150-155.

• 综述 • 上一篇    下一篇

多囊卵巢综合征的辅助生殖技术治疗

徐亚瑄,邓晓惠   

  1. 山东大学齐鲁医院
  • 收稿日期:2017-01-16 修回日期:2017-02-10 出版日期:2017-03-15 发布日期:2017-03-15
  • 通讯作者: 邓晓惠 E-mail:dxh0122@163.com

Assisted Reproduction Technology of Polycystic Ovary Syndrome:A Review

  • Received:2017-01-16 Revised:2017-02-10 Published:2017-03-15 Online:2017-03-15

摘要: 多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄期妇女常见的内分泌疾病,不孕是其主要的临床特点之一。在经过控制体重、调整生活方式、克罗米芬和芳香化酶抑制剂促排卵治疗、低剂量促性腺激素诱导排卵后,辅助生殖技术(assisted reproductive technology,ART)可能是治疗不孕的有效方法。但由于PCOS患者病因复杂,常伴有肥胖、代谢异常等,在实施ART时需根据患者的临床表现、辅助检查、患者对药物的反应性等给予个体化的治疗方案,进行纠正内分泌紊乱的预处理,同时要采取相应的措施预防卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS)等并发症的出现。本文综合国内外文献,就PCOS的助孕现状、ART在预处理、个性化方案和预防并发症三方面的新进展进行分别阐述。

关键词: 多囊卵巢综合征, 不孕症, 辅助生殖技术

Abstract: Polycystic ovary syndrome(PCOS) is a common endocrine disease in women of childbearing age, infertility is one of its clinical features. After weight control, lifestyle adjustment, clomiphene citrate and aromatase inhibitors induced ovulation, low-dose gonadotropin-induced ovulation, assisted reproductive technology(ART) may be an effective treatment. However, PCOS patients have complex etiologies, and often accompanied by obesity, metabolic abnormalities, individualized treatment should be taken according to the patient's clinical manifestations, examination results, and responses to drugs, such as correction of endocrine disorders, and prevention for OHSS and other complications. This paper reviews the current situation of ART for PCOS in pretreatment, individualized programs and the prevention of complications.

Key words: polycystic ovary syndrome, infertility, assisted reproductive technology

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