国际生殖健康/计划生育 ›› 2017, Vol. 36 ›› Issue (5): 392-395.

• 论著 • 上一篇    下一篇

紧急宫颈环扎术联合阿托西班在宫颈机能不全治疗中的临床价值

王秋明,武海英,党群   

  1.  450003  郑州,河南省人民医院妇产科
  • 收稿日期:2017-07-04 修回日期:2017-08-10 出版日期:2017-09-15 发布日期:2017-10-13
  • 通讯作者: 武海英,E-mail:hnsryfck@126.com E-mail:whysunnyzg@163.com

Clinical Effect of Emergency Cervical Cerclage Combined with Atosiban in the Treatment of Cervical Incompetence

WANG Qiu-ming,WU Hai-ying,DANG Qun   

  1. Department of Obstetrics and Gynecology,Henan Provincial People′s Hospital,Zhengzhou 450003,China
  • Received:2017-07-04 Revised:2017-08-10 Published:2017-09-15 Online:2017-10-13
  • Contact: WU Hai-ying,E-mail:hnsryfck@126.com E-mail:whysunnyzg@163.com

摘要: 目的:评价紧急宫颈环扎术联合阿托西班在治疗宫颈机能不全中的临床价值。方法:回顾性分析2013年1月—2015年12月于河南省人民医院因宫颈机能不全行紧急宫颈环扎手术,并使用阿托西班保胎的27例患者作为研究对象,观察紧急宫颈环扎术联合阿托西班治疗宫颈机能不全的疗效、妊娠结局和药物不良反应。结果:应用紧急宫颈环扎术联合阿托西班延长孕周(8.6±5.4)周,分娩孕周为(31.8±4.7)周,成功率为74.1%(20/27),应用阿托西班后抑制宫缩的有效率为62.9%(17/27)。仅有3例患者出现短时间轻微恶心、呕吐症状,1例出现轻微头痛,未出现因不良反应停止阿托西班治疗的情况。结论:紧急宫颈环扎术联合阿托西班能明显延长妊娠时间,妊娠结局良好,药物不良反应发生率低。

关键词: 环扎术, 宫颈, 宫颈功能不全, 阿托西班

Abstract: Objective:To investigate the clinical effect of the emergency cervical cerclage combined with atosiban in the treatment of cervical incompetence. Methods:A total of 27 patients with cervical incompetence, who were treated with emergency cervical cerclage and atosiban between January 2013 to December 2015, were analyzed retrospectively. Clinical effect, pregnancy outcome and maternal adverse events were assessed. Results:The combining treatment can effectively extend the gestational age for (8.6±5.4) weeks, with the delivery age (31.8±4.7) weeks and the total live birth rate 74.1% (20/27). The efficacy of atosiban on uterine contraction was 62.9% (17/27). Only four patients presented atosiban-related side effects, three of them presented with mild nausea and vomiting and one patient mild headache. No case discontinued atosiban because of drug-related side effects. Conclusions:The combination of atosiban with emergency cervical cerclage for the treatment of cervical incompetence can effectively extend the gestational age at delivery, and improve the pregnancy outcome.

Key words: Cerclage, cervical, Uterine cervical incompetence, Atosiban

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