国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2019, Vol. 38 ›› Issue (2): 124-126.

• 病例报告 • 上一篇    下一篇

体外受精-胚胎移植术后并发卵巢过度刺激综合征的病例分析：CA125异常升高

姜蕾，郝桂敏，许欣，万芳芳   

  1. 050000 石家庄，河北医科大学第二医院生殖医学科
  • 收稿日期:2018-10-18 修回日期:2018-12-05 出版日期:2019-03-15 发布日期:2019-03-15

Ovarian Hyperstimulation Syndrome after In Vitro Fertilization-Embryo Transfer, with Increased Level of CA125: A Case Report

JIANG Lei，HAO Gui-min，XU Xin，WAN Fang-fang   

  1. Department of Reproductive Medicine，The Second Hospital of Hebei Medical University，Shijiazhuang 050000，China
  • Received:2018-10-18 Revised:2018-12-05 Published:2019-03-15 Online:2019-03-15

PDF (PC)

9029

摘要： 卵巢过度刺激综合征（ovarian hyperstimulation syndrome，OHSS）是辅助生殖技术中常见的具有潜在危险的医源性并发症，严重者可危及生命。目前其发病机制尚不明确。临床治疗以预防为主，所以早期发现是关键。由于OHSS为自限性疾病，及时诊断治疗及随访，对患者至关重要，但目前尚无预测OHSS的金标准。本文报道1例体外受精-胚胎移植（IVF-ET）助孕后并发OHSS的患者，在取卵后血清中CA125异常增高。本文旨在探讨血清CA125与OHSS的相关性及临床意义，结合文献报道的类似病例，分析CA125作为OHSS风险预测、对症治疗和随访指标的可行性。

关键词: 卵巢过度刺激综合征, 受精, 体外, 胚胎移植, CA-125抗原, 病例报告

Abstract: Ovarian hyperstimulation syndrome (OHSS) is a common iatrogenic complication with potential risk in assisted reproductive technology, which can endanger life in severe cases. At present, the pathogensis is not clear. Prevention is the main clinical method, so the early detection is crucial. Due to OHSS is a self-limiting disease, timely diagnosis, treatment and follow-up visit are very important. However, there is no gold standard of OHSS prediction. We report an OHSS patient with the increased level of CA125 who undergo the IVF-ET treatment in this paper. With literature review, we therefore explore the correlation, and its clinical significance, between serum CA125 and OHSS, and discuss whether CA125 can be used as an OHSS parameter of risk evaluation, symptomatic treatment and follow-up visit.

Key words: Ovarian hyperstimulation syndrome, Fertilization in vitro, Embryo transfer, CA-125 antigen, Case reports