国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2017, Vol. 36 ›› Issue (6): 466-469.

• 论著 • 上一篇    下一篇

精子纤维鞘发育不良行胞浆内单精子注射成功妊娠一例

周世敏，刘能辉，邬玲仟   

  1. 410000  长沙，中南大学生命科学学院医学遗传学实验室（周世敏，邬玲仟）；中南大学湘雅医院生殖医学中心（刘能辉）
  • 收稿日期:2017-10-13 修回日期:2017-10-31 出版日期:2017-11-15 发布日期:2017-11-15

Pregnancy by ICSI Using the Sperm with Fibrous Sheath Dysplasia: A Case Report

ZHOU Shi-min，LIU Neng-hui，WU Ling-qian   

  1. Medical Genetics Laboratory，College of Life Science，Central South University，Changsha 410000，China（ZHOU Shi-min，WU Ling-qian）；Reproductive Medicine Center，Xiangya Hospital Central South University，Changsha 410008，China（LIU Neng-hui）
  • Received:2017-10-13 Revised:2017-10-31 Published:2017-11-15 Online:2017-11-15

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摘要： 精子纤维鞘发育不良（DFS）是一类罕见病，表现为严重的精子运动障碍和精子鞭毛形态异常，超微结构显示精子纤维鞘及轴丝组装异常。最近，本中心通过低渗肿胀试验（HOST）选择精子进行胞浆内单精子注射（ICSI）治疗患者1例，获得成功妊娠。

关键词: 不育, 男（雄）性, 精子注射, 细胞质内, 生殖技术, 辅助, 精子纤维鞘发育不良

Abstract: The dysplasia of sperm fibrous sheath (DFS) is a rare disease that is characterized by severe abnormality of sperm movement and flagella morphology. The ultrastructure observation can find the typical abnormality of sperm fibrous sheath and axial filament assembly. We recently got a successful pregnancy of DFS by intracytoplasmic single sperm injection (ICSI). In this case, the sperm selected by HOST method was used in ICSI.

Key words:  Infertility, male, Sperm injections, intracytoplasmic, Reproductive techniques, assisted, Dysplasia of the fibrous sheath