Abstract: Radiotherapy and chemotherapy are essential for the treatment of malignant tumors. However, chemoradiothery will have a negative impact on the reproductive function of young women, causing infertility. Before radiotherapy and chemotherapy, many fertility-preserving options can be provided, including ovarian transposition, embryo and oocyte cryopreservation, ovarian tissue cryopreservation , and drug-protective therapy. Transposition of the ovary to the outside of the hepatic flexure or splenic flexure of the colon can reduce the amount of radiation that the ovary bears. Oocyte and embryo cryopreservation is a mature technique, with its limitations. Cryopreservation of ovarian tissue is currently at clinical trial stage, with over 80 cases' reports. Inhibition of ovarian function with gonadotropin releasing hormone analogue during chemotherapy is a controversial method of preserving fertility. Oncologists and reproductive doctors need multidisciplinary collaboration to balance the fertility and the recurrence rate and mortality associated with cancer，so as to make the individualized treatment.

Key words: Fertility, Reproductive technology, assisted, Antineoplastic combined chemotherapy protocols, Radiotherapy, Women, Carcinoma