Abstract: Polycystic ovary syndrome (PCOS), a common endocrine disease in women of pregnancy age, is characterized by hyperinsulinemia, hyperandrogenism and/or anovulation. It spans the whole process of women's life. However, the etiology of PCOS is still unclear. Insulin resistance (IR) is one of the common metabolic disorders in patients with PCOS, in which hyperinsulinemia can lead to the changes in hormone levels, follicular growth restriction, endometrial receptivity, and increased abortion or infertility rates. The increased incidence of pregnancy complications, even anxiety, depression and other psychological problems, could be related with IR. PCOS combined with IR has attracted more and more attention in reproductive medicine.

Key words: Polycystic ovary syndrome, Insulin resistance, Fertility, Abortion