Analysis of Influencing Factors of Frozen-Thawed Embryo Transfer Pregnancy Outcome

doi:10.12280/gjszjk.20240149

Abstract

Abstract:

With the advancement of vitrification freezing technology, frozen-thawed embryo transfer (FET) plays a crucial role in assisted reproductive technology by preventing ovarian hyperstimulation syndrome, reducing ectopic pregnancy rates, and enhancing cumulative pregnancy rates. The proportion of FET cycles in assisted reproduction has been increasing annually, establishing FET as a key component of reproductive technologies. The outcome of FET pregnancies is influenced by various factors, including age, embryo quality, endometrial thickness, endometrial preparation protocols, DNA fragmentation, and Y chromosome microdeletions. Age, embryo quality, and endometrial receptivity are pivotal factors determining the success of FET treatments, directly impacting embryo development, implantation, and pregnancy success rates. Therefore, identifying the influencing factors of FET pregnancy outcome, so as to implement more precise, personalized and targeted prevention to improve pregnancy rates, has become a research hotspot. This review aims to summarize the relevant factors affecting the outcome of FET pregnancies, providing a reference for clinical decision.

Key words: Frozen-thawed embryo transfer, Reproductive techniques, assisted, Pregnancy outcome, Influencing factors, Pregnancy rate

LUO Sha-sha, WANG De-jing. Analysis of Influencing Factors of Frozen-Thawed Embryo Transfer Pregnancy Outcome[J]. Journal of International Reproductive Health/Family Planning, 2024, 43(5): 420-424.

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