Abstract: It was found that vaginitis was associated with HPV infection and cervical intraepithelial neoplasia（CIN）. The positive rate of trichomonas vaginitis in those HPV-positive patients was significantly higher than that in HPV-negative patients. The HPV clearance rate in both patients with the newly diagnosed vulvovaginal candidiasis and patients with recurrent vulvovaginal candidiasis was lower than that in patients without candida infections. The women with high-risk HPV persistent infections were more likely to have bacterial vaginosis than those with the high-risk HPV clearance，while bacterial vaginosis was related to the delayed clearance of high-risk HPV. The positive rate of bacterial vaginosis in CIN patients was higher than that in health women. It was also found that the HPV infection was related to the microbial constituent and pH value in vagina. The reduction, or absence, of vaginal lactobacilli were associated with HPV infection, CIN and cervical cancer. It is necessary to explore further all of above problems.

Key words: Vaginitis, Trichomonas vaginitis, Vaginosis, bacterial, Candidiasis, vulvovaginal, Papillomaviridae, Uterine cervical neoplasms