淫羊藿（苷）对男性生殖系统的作用和机制

doi:10.12280/gjszjk.20220051

摘要/Abstract

摘要：

淫羊藿是一种常用的中药材,淫羊藿苷是从淫羊藿中提取的一种黄酮类化合物,也是淫羊藿中最主要的活性物质。研究发现,淫羊藿苷具有促进成骨细胞的生成和活化、调节免疫、抗衰老和抗炎等多种功能。临床上淫羊藿（苷）用于治疗生殖系统、骨关节系统、呼吸系统、神经系统、心血管系统和免疫系统等多种疾病。淫羊藿（苷）对男性生殖系统的作用及机制主要包括具有雄性激素样作用,促进睾内睾酮的合成和分泌。淫羊藿（苷）通过改善精子发生的微环境、增强睾丸抗氧化作用促进精子生成,增加精子密度,改善精子活力,减缓生殖衰退。此外,淫羊藿（苷）可促进阴茎勃起,治疗勃起功能障碍及早泄。

关键词: 淫羊藿, 淫羊藿苷, 生殖器疾病,男（雄）性, 不育,男（雄）性, 治疗

Abstract:

Epimedium is a commonly used traditional Chinese medicine. Icariin as a flavonoid extracted from Epimedium is the main active substance in Epimedium. It is found that Icariin has many functions, such as promoting the formation and activation of osteoblasts, regulating immunity, anti-aging, anti-inflammatory and so on. Clinically, Epimedium(Icariin) is used to treat many diseases of reproductive system, bone and joint, respiratory system, nervous system, cardiovascular system, immune system and other. This paper summarizes the effects and mechanisms of Epimedium(Icariin) on male reproductive system. Epimedium(Icariin) plays an androgen-like effect by itself, and promotes the synthesis and secretion of testicular testosterone. Icariin can promote the production of sperm, increase sperm density, improve sperm motility, and slow down reproductive decline by improving the microenvironment of spermatogenesis and antioxidation. In addition, Epimedium(Icariin) is also used to treat the erectile dysfunction and premature ejaculation by promoting penile erection.

Key words: Epimedium brevicornum, Icariin, Genital diseases,male, Infertility,male, Therapy

李铖, 崔毓桂, 覃莲菊, 胡文军. 淫羊藿（苷）对男性生殖系统的作用和机制[J]. 国际生殖健康/计划生育, 2022, 41(3): 236-239.

LI Cheng, CUI Yu-gui, QIN Lian-ju, HU Wen-jun. The Effect and Mechanism of Epimedium (Icariin) on Male Reproductive System[J]. Journal of International Reproductive Health/Family Planning, 2022, 41(3): 236-239.

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