关键词: 肿瘤，多原发性, 宫颈胃型腺癌, 卵巢肿瘤, 治疗, 预后

Abstract:

A rare case of dual primary cancer which combined synchronous cervical adenocarcinoma with ovarian cancer was reported. The patient was a 56-year-old female. The main clinical manifestations were abnormal vaginal bleeding and lower abdominal pain. The levels of serum tumor markers were significantly elevated, pelvic CT showed the decreased patular enhancement of the posterior uterine wall, and electronic colposcopy biopsy showed the high-grade intraepithelial neoplasia of some glandular epithelium, more severe lesions not excluded. On June 2, 2020, the patient underwent the operation of exploratory laparotomy + enlarged hysterectomy + bilateral adnexectomy + pelvic adhesion release + pelvic lymph node dissection + abdominal drainage under endotracheal intubation and general anesthesia, and then underwent 6 times of chemotherapy and 1 time of pelvic three-dimensional conformal intensive radiotherapy. Later, she died due to the intestinal obstruction caused by tumor recurrence. The case data of cervical cancer combined with ovarian cancer were reviewed, in order to improve clinicians′ understanding of gynecological dual primary cancer.

Key words: Neoplasms, multiple primary, Gastric-type endocervical adenocarcinoma, Ovarian neoplasms, Therapy, Prognosis