甲状腺相关激素与子痫前期的相关性

doi:10.12280/gjszjk.20240112

摘要/Abstract

摘要：

子痫前期（preeclampsia）是一种起源于胎盘功能障碍，以母体内皮功能障碍为发病核心，以新发高血压和蛋白尿为主要症状的妊娠期疾病。甲状腺相关激素对女性的生殖代谢有重要作用，且妊娠期甲状腺疾病可导致多种不良妊娠结局。研究发现甲状腺相关激素与子痫前期密切相关。综述甲状腺相关激素参与子痫前期发病机制的途径及妊娠期甲状腺疾病与子痫前期的相关性，探究甲状腺相关激素在子痫前期发生发展中的作用。

关键词: 孕妇, 甲状腺素, 甲状腺疾病, 先兆子痫, 妊娠并发症, 胎盘

Abstract:

Preeclampsia (PE) is a pregnancy disorder originating from placental dysfunction, with maternal endothelial dysfunction at the core of pathogenesis. The main symptoms of PE are new-onset hypertension and proteinuria. Thyroid-related hormones have an important impact on reproduction and metabolism in women, while thyroid disorders can lead to a variety of adverse pregnancy outcomes. Thyroid-related hormones have been found to be strongly associated with PE. This paper will outline the pathways of thyroid-related hormones implicated in the pathogenesis of PE and examine the relationship between thyroid dysfunction and PE during pregnancy, with the aim of elucidating the potential role of thyroid-related hormones in the development and progression of PE.

Key words: Pregnant women, Thyroxine, Thyroid diseases, Pre-eclampsia, Pregnancy complications, Placenta

柳芳蕾, 冯晓玲. 甲状腺相关激素与子痫前期的相关性[J]. 国际生殖健康/计划生育杂志, 2024, 43(4): 348-352.

LIU Fang-lei, FENG Xiao-ling. The Correlation between Thyroid-Related Hormones and Preeclampsia[J]. Journal of International Reproductive Health/Family Planning, 2024, 43(4): 348-352.

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