国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2019, Vol. 38 ›› Issue (5): 382-388.

• 论著 • 上一篇    下一篇

膳食模式与精液质量参数相关性的Meta分析

黄嘉膂，林嘉盈，蔡任飞，宋宁，匡延平   

  1. 200011 上海交通大学医学院附属第九人民医院辅助生殖科（黄嘉膂，林嘉盈，蔡任飞，匡延平）；上海市生殖医学重点实验室（宋宁）
  • 收稿日期:2019-05-05 修回日期:2019-06-21 出版日期:2019-09-15 发布日期:2019-09-11
  • 通讯作者: 宋宁，E-mail：ningsong@outlook.com；匡延平：kuangyp1506@ sh9hospital.org E-mail:kuangyp1506@sh9hospital.org
  • 基金资助:
    国家自然科学基金（81501307）

Effect of Dietary Patterns on Semen Quality: A Meta-Analysis

HUANG Jia-lyu, LIN Jia-ying, CAI Ren-fei, SONG Ning, KUANG Yan-ping   

  1. Department of Assisted Reproduction, Shanghai Ninth People′s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China （ＨUANG Jia-lyu, LIN Jia-ying, CAI Ren-fei, KUANG Yan-pｉｎｇ）；Shanghai Key Laboratory of Reproductive Mediciｎｅ，Shanghai 200011，China （ＳＯＮＧ Ｎｉｎｇ）
  • Received:2019-05-05 Revised:2019-06-21 Published:2019-09-15 Online:2019-09-11
  • Contact: ＳＯＮＧ Ｎｉｎｇ，Ｅ－ｍａｉｌ：ｎｉｎｇｓｏｎｇ＠ｏｕｔｌｏｏｋ．ｃｏｍ；ＫＵＡＮＧ Ｙａｎ－ｐｉｎｇ，Ｅ－ｍａｉｌ： ｋｕａｎｇｙｐ１５０６＠ ｓｈ９ｈｏｓｐｉｔａｌ．ｏｒｇ E-mail:kuangyp1506@sh9hospital.org

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摘要： 目的：通过Meta分析评价膳食模式与精液质量参数的相关性。方法：遵循流行病学观察性研究Meta分析（MOOSE）指南，计算机检索PubMed、EMBASE、Web of Science和The Cochrane Library数据库，查找关于膳食模式与精液质量相关性的观察性研究，检索时间自建库至2018年6月。由2位研究者分别严格按照纳入与排除标准筛选文献、提取资料并评价文献质量，采用 Stata 12.0 软件进行 Meta 分析。结果：共纳入7篇文献，总样本量1 873例。Meta分析结果显示，健康膳食模式与非健康膳食模式相比，精子浓度（SMD=0.20，95%CI：0.07～0.33，P=0.003）、精子总数（SMD=0.27，95%CI：0.07～0.46，P=0.008）和精子前向运动率（SMD=0.46，95%CI：0.24～0.69，P＜0.001）提高，差异有统计学意义；精液量（SMD=-0.20，95%CI：0.82～0.42，P=0.525）、精子正常形态率（SMD=-0.01，95%CI：-0.14～0.12，P=0.890）和精子总活力（SMD=-0.10，95%CI：-0.55～0.36，P=0.680）差异无统计学意义。结论：健康膳食模式与男性精子浓度、精子总数和精子前向运动率等精液质量参数有正相关关系。

关键词: Meta分析, 膳食疗法, 精液分析, 不育, 男（雄）性

Abstract: Objective：To evaluate the effect of dietary patterns on semen quality by a meta-analysis. Methods: This study was conducted in accordance with the Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines. All of observational studies assessing the association between dietary patterns and semen quality parameters were searched by PubMed, EMBASE, Web of Science and the Cochrane library databases from inception to June 2018. The studies were screened according to the inclusion and exclusion criteria by two researchers independently, followed by data extraction and quality evaluation. The Stata 12.0 software was used for Meta-analysis. Results: A total of 7 literatures involving 1 873 participants were included. The Meta-analysis results showed that the healthy dieatry pattern was associated with the increased sperm concentration (SMD=0.20, 95%CI: 0.07-0.33, P=0.003), count (SMD=0.27, 95%CI: 0.07-0.46, P=0.008) and progressive motility (SMD=0.46, 95%CI: 0.24-0.69, P＜0.001), and that it was not associated with semen volume (SMD=-0.20, 95%CI: -0.82-0.42, P=0.525), sperm morphology (SMD=-0.01, 95%CI: -0.14-0.12, P=0.890) and total motility (SMD= -0.10, 95%CI: -0.55-0.36, P=0.680). Conclusion: The healthy dietary pattern is beneficial to improve semen quality.

Key words: Meta-analysis, Dietary therapy, Semen analysis, Infertility, male