Journal of International Reproductive Health/Family Planning ›› 2021, Vol. 40 ›› Issue (5): 402-406.doi: 10.12280/gjszjk.20210042

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Research Progress on Oxidative Stress and Reproductive Related Diseases

JIANG Nan, MA Rui-hong, ZHAO Xiao-li, XIA Tian()   

  1. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
  • Received:2021-01-23 Published:2021-09-15 Online:2021-09-29
  • Contact: XIA Tian E-mail:xiatian76@163.com

Abstract:

Reactive oxygen species (ROS) is the product of the reaction between oxygen and electrons. The appropriate level of ROS and the oxidative stress balance play an important role in maintaining physiological function. When ROS was produced too much or the ability to eliminate ROS was weakened, the increased oxidative stress (OS) could lead to a variety of infertility-related diseases. OS is involved in the occurrence and development of polycystic ovary syndrome, endometriosis, recurrent abortion and other diseases, as well as the prognosis of these diseases. In addition to being involved in female reproductive-related diseases, OS can also reduce semen quality and affect male reproductive function. This article reviews the pathogenesis of oxidative stress and its effect on reproduction-related diseases.

Key words: Oxidative stress, Reactive oxygen species, Polycystic ovary syndrome, Endometriosis, Abortion, habitual, Infertility, male