Journal of International Reproductive Health/Family Planning ›› 2016, Vol. 35 ›› Issue (3): 241-244.

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The Clinical Application of Anti-Müllerian Hormone in Female Reproduction

LIU Zhen-xing,LI Hong   

  1. Nanjing Medical University,Nanjing 210029,China(LIU Zhen-xing); Suzhou Hospital Affiliated to Nanjing Medical University,Suzhou 215002,Jiangsu Province,China(LI Hong)
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-05-15 Online:2016-05-15
  • Contact: LI Hong

Abstract: The number and quality of oocyte decline with age. However, the fertility varies significantly even among women of the same age. Many measures have been developed to predict the response to ovarian stimulation and the reproductive potential. Anti-Müllerian hormone (AMH), a glycoprotein secreted by the granulosa cells of small growing follicles, can indirectly reflect the number of follicles in the primordial follicle pool and thus reflect the ovarian reserve. AMH as a practical indicator has been used to predict the ovarian response in IVF cycles, to predict the age of menopause, and to assess the ovarian reserve after iatrogenic injury as well. It has also been proposed as a surrogate for antral follicle count (AFC) in the diagnosis of polycystic ovary syndrome (PCOS).

Key words: Anti-Mullerian hormone, Reproductive techniques, assisted, Ovarian failure, premature, Ovarian neoplasms, Polycystic ovary syndrome