Endometrial Stem/Progenitor Cells and the Pathogenesis of Endometriosis

doi:10.12280/gjszjk.20200720

Abstract

Abstract:

The endometrial stem/progenitor cells are new targets for the study of the pathogenesis of endometriosis. According to their surface markers and functions in human body, endometrial stem/progenitor cells can be divided into four subgroups: endometrial epithelial progenitor cells, endometrial mesenchymal stem cells, side population cells, niche cells. The discovery of endometrial stem/progenitor cells has improved the Sampson′s theory of retrograde menstruation, and provided a new and reasonable explanation for the pathogenesis of adolescent endometriosis. The further study of endometrial stem/progenitor cells will provide a new possibility for the diagnosis and treatment of endometriosis.

Key words: Endometriosis, Endometrium, Stem cells, Mesenchymal stromal cells

DAI Lei, MAO Yun-dong. Endometrial Stem/Progenitor Cells and the Pathogenesis of Endometriosis[J]. Journal of International Reproductive Health/Family Planning, 2021, 40(4): 319-322.

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