Journal of International Reproductive Health/Family Planning ›› 2018, Vol. 37 ›› Issue (2): 154-158.

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Research Progress of Triglyceride Metabolism During Pregnancy

CHEN Meng-fan,CHEN Dan-qing   

  1. Department of Obstetrics and Gynecology,Women′s Hospital,School of Medicine,Zhejiang University,Hangzhou 310006,China
  • Received:2017-12-12 Revised:2018-01-11 Published:2018-03-15 Online:2018-03-15
  • Contact: CHEN Dan-qing,E-mail:chendq@zju.edu.cn E-mail:chendq@zju.edu.cn

Abstract: Triglyceride as a main component of lipids in human body  can be hydrolyzed by lipoprotein lipase into free fatty acids and glycerins. Triglyceride also participates in energy supply for mother and fetus, and fetal development during pregnancy. Recently, increasing studies have shown that the level of triglyceride in pregnant women was remarkably higher than in non-pregnant women, and  that the level of triglyceride was increased with the progress of pregnancy. Interestingly, the level of triglyceride was changed in those women with gestational complications such as gestational diabetes mellitus, pre-eclampsia, intrahepatic cholestasis of pregnancy, premature delivery and gestational acute pancreatitis. This article discussed the relationships between the altered triglyceride level and gestational complications such as gestational diabetes mellitus, pre-eclampsia and intrahepatic cholestasis of pregnancy. The related mechanism and follow-up visit were also included. It is important to develop the internationally-recognized range of triglyceride with regional differences and the individualized monitoring and treatment guidelines. The management of triglyceride level during pregnancy is of great importance.

Key words: Triglycerides, Diabetes, gestational, Pre-eclampsia, Cholestasis, intrahepatic, Pregnancy complications, Premature birth