Abstract: Objective: To investigate the relationship between endometriosis without ovary lesions and ovarian reserve function. Methods：Retrospective analysis of 100 infertile women who underwent in vitro fertilization（IVF）from January 2007 to January 2009 in Centre for Reproductive Medicine, Anhui Provincial Hospital. Patients were divided into two groups: group A contained 50 cases of endometriosis without ovary lesions diagnosed by laparoscopy, group B (control group) contained 50 cases of tubal obstruction. Serum FSH, LH, E2 hormone and antral follicular count (AFC) were measured on the day 3 of menses. Number of retrieved oocytes, embryo quality, cycle cancellation rate and clinical pregnancy rates were compared between two groups. Results： Compared to the control group, group A has higher levels of the basis FSH, FSH / LH ratio, E2 and Gn dosage, and cycle cancellation rate, but less AFC and retrieved oocytes,. The differences are statistically significant. Serum LHaccelerate hormone on the day 3 of menses, high-quality embryo rate and pregnancy rate are not different between two groups. Conclusion：Ovarian reserve failure can be accelerated by endometriosis. Women with endometriosis should be advised to conceive and give birth to a child as soon as possible, if necessary, the assisted reproductive technology maybe the best choice.

Key words: Endometriosis, Ovarian reserve, In vitro fertilization, High-quality embryo rate, Pregnancy rate