国际生殖健康/计划生育 ›› 2018, Vol. 37 ›› Issue (6): 481-485.

• 综述 • 上一篇    下一篇

腹型肥胖对精液参数影响的研究进展

千丽,郭艺红   

  1. 450000  郑州大学第一附属医院
  • 收稿日期:2018-09-06 修回日期:2018-09-28 出版日期:2018-11-15 发布日期:2018-11-15
  • 通讯作者: 郭艺红,E-mail:13613863710@163.com E-mail:13613863710@163.com
  • 基金资助:
    国家自然科学基金(81571409);河南省医学科技攻关计划省部共建项目(201701005)

Effect of Abdominal Obesity on Semen Parameters:A Review

QIAN Li,GUO Yi-hong   

  1. The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China
  • Received:2018-09-06 Revised:2018-09-28 Published:2018-11-15 Online:2018-11-15
  • Contact: GUO Yi-hong,E-mail:13613863710@163.com E-mail:13613863710@163.com

摘要: 中国育龄男性腹型肥胖比例持续增加。流行病学研究表明,腹型肥胖对男性精液质量有负面影响。综述腹型肥胖评价方式、腹型肥胖对精液质量影响机制及腹型肥胖的干预措施,总结近年来的研究成果。中国男性腰围>85 cm、腰高比>50可被认为是腹型肥胖。计算机断层扫描(CT)、磁共振成像(MRI)和双能X线吸收测量法(DEXA)可以更准确地评价内脏脂肪含量。腹型肥胖可通过生殖激素、氧化应激、脂肪因子、物理因素、凋亡等方式影响精液质量。此外,腹型肥胖还可以影响勃起功能。高强度间歇运动可以减少内脏脂肪,辅以维生素D可以改善脂肪组织炎症。腹型肥胖与男性精液质量部分关联机制尚缺乏深入细致的研究,如何改善腹型肥胖来提高男性精液质量缺乏大型临床对照研究。

关键词: 肥胖症, 腹部, 精液, 氧化性应激, 炎症

Abstract: Abdominal obesity among men of childbearing age in China continues to increase. Epidemiology showed the negative effect of abdominal obesity on semen quality. In this paper, the evaluation methods of abdominal obesity, the effect and mechanism of abdominal obesity on semen quality, as well as the intervention, were reviewed. The waist circumference >85 cm and the ratio of waist to height >50 in China can be used as the two parameters of abdominal obesity. CT, MRI and DEXA can be used to evaluate visceral fat content more accurately. Abdominal obesity can affect semen quality by reproductive hormones, oxidative stress, fat factors, physical factors, apoptosis and so on. In addition, abdominal obesity can also affect erectile function. High intensity intermittent exercise can reduce visceral fat, and supplement with vitamin D can improve adipose tissue inflammation. However, the effect of abdominal obesity on semen quality and potential mechanisms should be studied more deeply and carefully in future, including the clinical controlled study with large samples.

Key words: Obesity, Abdomen, Semen, Oxidative stress, Inflammation